I’m interested in understanding the onset and progression of cognitive and behavioural dysfunction in neurodegenerative diseases, particularly motor neuron disease and frontotemporal dementia. I'm also interested in how other factors such as genetic status and psychiatric symptoms contribute to the presence neuropsychological impairment in neurodegenerative diseases.
Associate Fellowship - Advanced HE
MND Learn
MND Scotland
Presented research to people with MND and their family members at the MND Scotland event.
Alignment of concepts, terminology and operational definitions of prodromal state
Invited presentation at the Phenotype and Biology of ALS Frontotemporal Disorders workshop.
Characterising behavioural symptoms in ALS: The ECAS Extended Behavioural Interview
MND Association International Symposium
Mild Cognitive Impairment in presymptomatic MND
University of Edinburgh
Presentation at the Euan MacDonald Tribute Symposium to academics and members of the public.
Committee Member - ICNALS: International Consortium for Neuropsychology in ALS
Committee Member - INITIATE: Implementing Training in ALS/MND Through Education
Committee Member - Phenotype and Biology of ALS Frontotemporal Spectrum Disorders Workshop
British Neuropsychological Society
Article
De Vocht J, Costello E, McHutchison C, Radakovic R, Foucher J, McMackin R, Peelo C, van den Berg L, Hardiman O, Van Damme P, Pender N, Abrahams S, Lulé D & first ICNALS Workshop (2026) Prioritizing neuropsychological research and care in Amyotrophic Lateral Sclerosis (ALS): building an international neuropsychological framework for ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. https://doi.org/10.1080/21678421.2025.2610290
Article
Utility of patient subgrouping in ALS clinical trials: a World Federation of Neurology white paper
Rosenfeld J, Abrahams S, McHutchinson C, Ajroud-Driss S, Weber M, Paganoni S, Mitsumoto H, Genge A, Grosskreutz J, Van Den Berg L, Andrews J & Kiernan MC (2025) Utility of patient subgrouping in ALS clinical trials: a World Federation of Neurology white paper. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. https://doi.org/10.1080/21678421.2025.2593308
Article
Jaime Garcia D, Makin SDJ, McHutchison CA, Cvoro V, Valdés Hernández MDC, Sakka E, Chappell FM, Doubal F & Wardlaw JM (2025) Functional, Cognitive, Physical, and Vascular Outcomes 9 Years After Lacunar and Mild Cortical Ischemic Stroke. Neurology, 105 (5), Art. No.: e214018. https://doi.org/10.1212/wnl.0000000000214018
Article
The Basis of Cognitive and Behavioral Dysfunction in Amyotrophic Lateral Sclerosis
Bampton A, McHutchison C, Talbot K, Benatar M, Thompson AG & Turner MR (2024) The Basis of Cognitive and Behavioral Dysfunction in Amyotrophic Lateral Sclerosis. Brain and Behavior, 14 (11), Art. No.: e70115. https://doi.org/10.1002/brb3.70115
Article
Benatar M, Macklin EA, Malaspina A, Rogers M, Hornstein E, Lombardi V, Renfrey D, Shepheard S, Magen I, Cohen Y, Granit V, Statland JM, Heckmann JM, Rademakers R & McHutchison CA (2024) Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis. eBioMedicine, 108, Art. No.: 105323. https://doi.org/10.1016/j.ebiom.2024.105323
Article
Benatar M, Wuu J, Huey ED, McMillan CT, Petersen RC, Postuma R, McHutchison C, Dratch L, Arias JJ, Crawley A, Houlden H, McDermott MP, Cai X, Thakur N & Boxer A (2024) The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology. Nature Reviews Neurology, 20, pp. 364-376. https://doi.org/10.1038/s41582-024-00961-z
Article
Temporal course of cognitive and behavioural changes in motor neuron diseases
McHutchison CA, Wuu J, McMillan CT, Rademakers R, Statland J, Wu G, Rampersaud E, Myers J, Hernandez JP, Abrahams S & Benatar M (2024) Temporal course of cognitive and behavioural changes in motor neuron diseases. Journal of Neurology, Neurosurgery & Psychiatry, 95, pp. 316-324. https://doi.org/10.1136/jnnp-2023-331697
