Exposure assessment for a population-based case-control study combining a job-exposure matrix with interview data

Citation

Semple S, Dick F, Cherrie J, Seaton A, Haites N, Osborne A, Grant F, Joshi S, Adiakpan N, Sutherland S, Prescott G, Scott N, Counsell C, Coleman R & Primrose W (2004) Exposure assessment for a population-based case-control study combining a job-exposure matrix with interview data. Scandinavian Journal of Work, Environment and Health, 30 (3), pp. 241-248. https://www.scopus.com/inward/record.uri?eid=2-s2.0-3142661278&doi=10.5271%2fsjweh.785&partnerID=40&md5=2f0db5a8de3f9a6613bad6cffca99dff; https://doi.org/10.5271/sjweh.785

Abstract
Objectives. A system that combines the ease of use of a job-exposure matrix while taking into account job-specific data is needed. This study aimed to produce a detailed method for combining interview data with expert assessments for a large population-based case-control study of Parkinson's disease. Method. An interview-administered core questionnaire with a series of questions that triggers substance-specific questionnaires to gather information on key parameters is administered. Using a job-exposure matrix to generate base estimates, assessors can modify this estimate of exposure intensity using worker-specific data such as the use of control measures, reports of substance-specific acute symptoms, and the quantity of material being processed. Detailed guidance for making adjustments to exposure estimates for these modifiers is presented. Results. The method has been partially validated through the use of a comparison of estimates for a separate cohort with previously validated exposure reconstructions. Agreement was high, with a Spearman's rho of 0.89 (P

Journal
Scandinavian Journal of Work, Environment and Health: Volume 30, Issue 3

People

Professor Sean Semple

Professor, Institute for Social Marketing