Citation Weidmann M, Faye O, Faye O, Abd El Wahed A, Patel P, Batejat C, Manugerra JC, Adjami A, Niedrig M, Hufert FT & Sall AA (2018) Development of mobile laboratory for viral hemorrhagic fever detection in Africa. Journal of Infectious Diseases, 218 (10), pp. 1622-1630. https://doi.org/10.1093/infdis/jiy362
In order to enable local response to viral haemorrhagic fever outbreaks a mobile laboratory transportable on commercial flights was developed.
The development progressed from use of mobile real time RT-PCR to mobile Recombinase Polymerase Amplification (RT-RPA). The various stages of the mobile laboratory development are described.
A brief overview of its deployments, which culminated in the first on site detection of Ebola virus disease (EVD) in March 2014 and a successful use in a campaign to roll back EVD cases in Conakry in the West-Africa Ebola virus outbreak are described.
The developed mobile laboratory successfully enabled local teams to perform rapid viral haemorrhagic fever disgnostics.
Keywords Viral haemorragic fever virus; Recombinase polymerase amplification; SmartCycler; Mobile laboratory; Ebola virus disease; point of care; laboratory suitcase
Journal Journal of Infectious Diseases: Volume 218, Issue 10
Weidmann, Manfred; Faye, Ousmane; Faye, Oumar; Abd El Wahed, Ahmed; Patel, Pranav; Batejat, Christophe; Manugerra, Jean Claude; Adjami, Aimee; Niedrig, Matthias; Hufert, Frank T; Sall, Amadou A
European Commission and Welcome Trust programme: Research for Health in Humanitarian Crises (R2HC)