Improving Adherence to Medication in Stroke Survivors (IAMSS): a randomised controlled trial: study protocol



O'Carroll R, Martin D, Johnston M & Sudlow C (2010) Improving Adherence to Medication in Stroke Survivors (IAMSS): a randomised controlled trial: study protocol. BMC Neurology, 10, Art. No.: 15.;

Background: Adherence to therapies is a primary determinant of treatment success, yet the World Health Organisation estimate that only 50% of patients who suffer from chronic diseases adhere to treatment recommendations. In a previous project, we found that 30% of stroke patients reported sub-optimal medication adherence, and this was associated with younger age, greater cognitive impairment, lower perceptions of medication benefits and higher specific concerns about medication. We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke. Methods/Design: Thirty patients will be allocated to a brief intervention (2 sessions) and 30 to treatment as usual. The primary outcome will be adherence measured over 3 months using Medication Event Monitoring System (MEMS) pill containers which electronically record openings. Secondary outcomes will include self reported adherence and blood pressure. Discussion: This study shall also assess uptake/attrition, feasibility, ease of understanding and acceptability of this complex intervention. Trial Registration: Current Controlled Trials ISRCTN38274953

; Health Psychological aspects; Personality; Practice Management organization & administration

BMC Neurology: Volume 10

FundersChief Scientist Office
Publication date31/12/2010
PublisherBioMed Central Ltd.
Publisher URL

People (1)


Professor Ronan O'Carroll
Professor Ronan O'Carroll

Professor, Psychology

Projects (1)

Research programmes

Research themes