Short Term Plasticity Provides Temporal Filtering at Chemical Synapses

Citation

Graham B & Stricker C (2008) Short Term Plasticity Provides Temporal Filtering at Chemical Synapses. In: Kurkova V, Neruda R & and KJ (eds.) Artificial Neural Networks - ICANN 2008: 18th International Conference, Prague, Czech Republic, September 3-6, 2008, Proceedings, Part II. Lecture Notes in Computer Science, 5164. 18th International Conference on Artificial Neural Networks –ICANN 2008, Prague, Czech Republic, 03.09.2008-06.09.2008. Berlin, Germany: Springer-Verlag, pp. 268-276. http://link.springer.com/chapter/10.1007%2F978-3-540-87559-8_28; https://doi.org/10.1007/978-3-540-87559-8_28

Abstract
Chemical synapses exhibit a wide range of mechanisms that modulate the postsynaptic response due to presynaptic action potentials (APs) as a function of the arrival pattern of the presynaptic APs. Here we demonstrate that combinations of depression, facilitation and frequency-dependent recovery will give synapses that are either sensitive to the steady-state input signal, or to the onsets and offsets of signal transients. In addition, a synapse may be tuned to preferentially respond to low frequency modulation of an input signal.

Keywords
Synaptic transmission; Short term plasticity; Depression; Facilitation

People

Professor Bruce Graham

Emeritus Professor, Computing Science