Long-term course of cognitive impairment in schizophrenia



Morrison G, O'Carroll R & McCreadie R (2006) Long-term course of cognitive impairment in schizophrenia. British Journal of Psychiatry, 189 (6), pp. 556-557.

The aim of this study was to examine the long-term course of cognitive impairment in people with schizophrenia. Forty-three people with schizophrenia were followed up over an average of 33 years along with a control group of 12 matched individuals free from psychosis. Cognitive function was assessed at baseline and follow-up. The participants with schizophrenia were found to show impairment in verbal and non-verbal intelligence at baseline compared with estimated premorbid scores, this was not found in the control group. At follow-up there was a significant decline in non-verbal intelligence over time in participants with schizophrenia compared with controls (P=0.007). This differential change over time was not seen in verbal intelligence (P= 0.318).

British Journal of Psychiatry: Volume 189, Issue 6

Publication date31/12/2006
PublisherThe Royal College of Psychiatrists

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Professor Ronan O'Carroll
Professor Ronan O'Carroll

Professor, Psychology

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