Bell JG, Cowey CB, Adron JW & Pirie BJS (1987) Some effects of selenium deficiency on enzyme activities and indices of tissue peroxidation in Atlantic salmon parr (Salmo salar). Aquaculture, 65 (1), pp. 43-54. https://doi.org/10.1016/0044-8486%2887%2990269-9
Two groups of Atlantic salmon (Salmo salar), mean weight 6 g, were given diets of differing selenium content (deficient 0.017 mg Se/kg; supplemented 0.944 mg Se/kg) and adequate vitamin E content (40 mg α-tocopheryl acetate/kg) for 28 weeks. The final weight and packed cell volume of salmon given the Se-supplemented diet were significantly greater than those of the Se-deprived fish. Blood vitamin E concentrations, and liver, blood and brain Se concentrations were all significantly lowered in Se-deficient salmon. No gross pathologies were observed but pathology was evident in pancreatic tissue (loss of integrity in endoplasmic reticulum and increased vacuolation) from Se-deficient salmon. Glutathione peroxidase (EC.220.127.116.11) activity was greatly reduced in liver of the Se-deficient salmon although there was no indication of any compensatory non Se-dependent glutathione peroxidase activity. Hepatic glutathione S-transferase (EC.18.104.22.168) activity, plasma pyruvate kinase (EC.22.214.171.124) activity, erythrocyte fragility and kidney reduced glutathione were all increased in Se deficiency.
Aquaculture: Volume 65, Issue 1