Citation Aalten P, Verhey FRJ, Boziki M, Bullock RA, Byrne EJ, Camus V, Caputo M, Collins D, De Deyn PP, Elina K, Frisoni G, Girtler N, Holmes C, Hurt C & Reynish E (2007) Neuropsychiatric syndromes in dementia - Results from the European Alzheimer Disease Consortium: Part I. Dementia and Geriatric Cognitive Disorders, 24 (6), pp. 457-463. https://doi.org/10.1159/000110738
Abstract Background/Aims: The aim of this study was to identify neuropsychiatric subsyndromes of the Neuropsychiatric Inventory in a large sample of outpatients with Alzheimer's disease (AD).
Methods: Cross-sectional data of 2,354 patients with AD from 12 centres from the European Alzheimer's Disease Consortium were collected. Principal component analysis was used for factor analysis.
Results: The results showed the presence of 4 neuropsychiatric subsyndromes: hyperactivity, psychosis, affective symptoms and apathy. The subsyndrome apathy was the most common, occurring in almost 65% of the patients.
Conclusion: This large study has provided additional robust evidence for the existence of neuropsychiatric subsyndromes in AD.