Minimum inhibitory concentrations of selected antimicrobial compounds against Flavobacterium psychrophilum the causal agent of rainbow trout fry syndrome (RTFS)

Citation

Rangdale RE, Richards R & Alderman DJ (1997) Minimum inhibitory concentrations of selected antimicrobial compounds against Flavobacterium psychrophilum the causal agent of rainbow trout fry syndrome (RTFS). Aquaculture, 158 (3-4), pp. 193-201. https://doi.org/10.1016/S0044-8486%2897%2900202-0

Abstract
The in vitro susceptibilities of 48 isolates of Flavobacterium psychrophilum, the causal agent of rainbow trout fry syndrome (RTFS), to the major fish farming antimicrobial agents and to a selection of other antimicrobials were assessed using a broth microdilution method. These data were used along with previous published antibiograms for F. psychrophilum, drug serum and tissue levels and reports clinical effect in an attempt to predict the probable therapeutic efficacy. The results indicated that resistance to the most commonly used antimicrobial compounds was significant, but that doxycycline, sarafloxacin, enrofloxacin and florfenicol showed potential as candidate compounds for in vivo trials.

Keywords
Flavobacterium psychrophilum; Cytophaga psychrophila; Rainbow trout fry syndrome (RTFS); Antimicrobial susceptibility; Bacterial resistance

Journal
Aquaculture: Volume 158, Issue 3-4

People

Professor Randolph Richards

Emeritus Professor, Institute of Aquaculture