Timmons JA, Szkop KJ & Gallagher IJ (2015) Multiple sources of bias confound functional enrichment analysis of global -omics data. Genome Biology, 16 (1), Art. No.: 186. https://doi.org/10.1186/s13059-015-0761-7
Serious and underappreciated sources of bias mean that extreme caution should be applied when using or interpreting functional enrichment analysis to validate findings from global RNA- or protein-expression analyses.
Genome Biology: Volume 16, Issue 1