Article

Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey

Details

Citation

Wells M, Swartzman S, Lang H, Cunningham M, Taylor L, Thomson J, Philp J & McCowan C (2016) Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey. Supportive Care in Cancer, 24 (6), pp. 2463-2472. https://doi.org/10.1007/s00520-015-3045-6

Abstract
Purpose This study aimed to assess quality of life (QoL) in head and neck cancer (HNC) survivors and determine factors predic- tive of poor QoL in the first 5 years after the end of treatment. Methods A cross-sectional survey, including the Quality of Life in Adult Cancer Survivors (QLACS) measure, was sent to HNC survivors in three Scottish health regions, with re- sponses linked to routinely collected clinical data. Indepen- dent sample t tests, ANOVAs, Pearson correlations and mul- tiple hierarchical regressions were used to explore associa- tions between and to determine the contribution made by de- mographic, lifestyle and clinical factors to predicting ‘generic’ and ‘cancer-specific’ quality of life. Results Two hundred eighty patients (65 %) returned ques- tionnaires. After adjustment, multivariate analysis showed that younger age, lower socio-economic status, unemployment and self-reported comorbidity independently contributed to poorer generic and cancer-specific quality of life. In addition to these factors, having had a feeding tube or a diagnosis of oral cavity cancer were independently predictive of poorer cancer-specific quality of life. Conclusions Socio-economic factors and comorbidity are im- portant predictors of QoL in HNC survivors. These factors and the detrimental long-term effects of feeding tubes need further attention in research and practice.

Keywords
Quality of life; Head and neck cancer; Survivors; Socio-economic status; Feeding tube

Journal
Supportive Care in Cancer: Volume 24, Issue 6

StatusPublished
FundersMacmillan Cancer Support
Publication date30/06/2016
Publication date online11/12/2015
Date accepted by journal29/11/2015
URLhttp://hdl.handle.net/1893/22623
PublisherSpringer
ISSN0941-4355
eISSN1433-7339

People (2)

People

Dr Margaret Cunningham
Dr Margaret Cunningham

Research Fellow

Professor Mary Wells
Professor Mary Wells

Honorary Professor, NMAHP

Projects (1)

Unmet needs in head and neck cancer survivors
PI: