For people who are at greater risk of cancer due to a family history of the disease (which may reflect shared genetic and behavioral profiles) it is important to follow recommendations for cancer screening and lifestyle. This study aimed to assess the feasibility and acceptability of delivering a 12-week lifestyle intervention programme (LivingWell) for people with a family history of BC and CRC initiated within the clinic setting in order to inform the design of a definitive randomised control trial (RCT) to assess the clinical and cost-effectiveness of this intervention. The primary outcome of the future RCT will be weight loss (with secondary outcomes of alcohol intake, physical activity, dietary intake, psycho-social parameters, weight monitoring procedures and cost effectiveness). This was done through a two arm, two-centre, randomised feasibility study of the LivingWELL intervention versus usual care.
Anderson AS, Dunlop J, Gallant S, Macleod M, Miedzybrodzka Z, Mutrie N, O'Carroll R, Stead M, Steele R, Taylor RS, Vinnicombe S & Berg J (2018) Feasibility study to assess the impact of a lifestyle intervention ('LivingWELL') in people having an assessment of their family history of colorectal or breast cancer. BMJ Open, 8 (2), Art. No.: e019410. https://bmjopen.bmj.com/content/8/2/e019410
Anderson AS, Caswell S, Macleod M, Steele R, Berg J, Dunlop J, Stead M, Eadie D & O'Carroll R (2017) Health behaviors and their relationship with disease control in people attending genetic clinics with a family history of breast or colorectal cancer. Journal of Genetic Counselling, 26 (1), pp. 40-51. https://doi.org/10.1007/s10897-016-9977-2