Our research spans the spectrum from healthy active individuals to clinical populations across all sections of the lifespan. The facilities and expertise within the team allow us to address fundamental and applied research questions at the cellular/molecular level using cell culture models through to molecular and enzymatic analysis of tissue samples obtained using tissue biopsy techniques, or genetic and epigenetic analyses from tissue or blood samples, as well as whole body human physiological measurements of cardiovascular, respiratory, renal and metabolic function using a variety of techniques. The work of the group is centred on two key areas:
Developing a greater understanding of muscle physiology and function in health and disease throughout the life course.
Developing a greater understanding of the impact of nutrition and exercise on health and sport performance.
The Physiology, Exercise and Nutrition Research Group is led by Prof Kevin Tipton who is a world leading expert in protein nutrition and metabolism with an emphasis on athletes and vulnerable populations (e.g. obese, elderly, and healthy volunteers).
Members of the research team are:
Dr Stuart Galloway Head of Sport; whose research focuses regulation of fluid balance and on the impact of nutritional and exercise stimuli on carbohydrate and fat metabolism in human skeletal muscle;
Dr Angus Hunter whose work focuses on neuromuscular control in clinical and athletic populations;
Dr Colin Moran Director of Laboratories; who aims to understand how genetic, epigenetic and environmental variations interact and contribute to the development of ageing related diseases (such as dementia), metabolic disease, exercise capacity and athletic ability in humans;
Dr Naomi Brooks investigates satellite cells (muscle stem cells) and molecular pathways (such as myostatin) in various conditions of muscle atrophy;
Dr Iain Gallagher uses high throughput technology to examine mRNA and microRNA changes in a variety of biological contexts spanning pathology, development and immunology;
Dr Oliver Witard focuses on the adaptive response of human skeletal muscle to exercise and nutrition, in particular protein feeding;
Dr Lee Hamilton a molecular exercise physiologist with a primary research goal to understand the molecular basis of skeletal muscle plasticity;
Dr Niels Vollaard has an interest in the health benefits of exercise in general, and of the effects of high-intensity interval training (HIT) in particular.
We have extensive research facilities available to the group and the team is supported by two technical staff, one with expertise in analytical chemistry (Gillian Dreczkowski), and one with electronics/programming expertise (Chris Grigson). Our group currently has two research assistants and twenty postgraduate research students (MPhil/PhD).