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Barnett KN, Ogston SA, McMurdo MET, Morris AD & Evans J (2007) An 11 year follow-up study of mortality and cause of death in 11,125 people newly diagnosed with Type 2 diabetes (Conference Abstract), Diabetic Medicine, 24 (Supplement 1), pp. 12-12.
Aim: To compare mortality between patients diagnosed with Type 2 diabetes and non-diabetic comparators.
Methods: An observational cohort study was conducted in Tayside, Scotland, using electronically linked data from the DARTS database (clinical information and death certification data). Survival analyses were conducted using Cox regression to examine differences in overall mortality and primary cause of death between patients diagnosed with Type 2 diabetes in 1993-2005 and non-diabetic patients (patients registered in General Practice, matched for age, sex and practice). These were stratified according to age at diagnosis. Hazard ratios were also calculated for mortality from diabetic complications.
Results: There were 11,125 diabetic patients and 22,250 nondiabetic patients, of which 1777 (16%) and 2796 (12.6%) respectively died during the 11-year follow-up. The overall hazard ratio for mortality for patients with Type 2 diabetes compared to non-diabetic patients was 1.324 (95%CI 1.250-1.403) controlling for deprivation. It decreased from 1.205 (1.105-1.315) for patients diagnosed over 75 years to 5.704 (2.665-12.209) for patients diagnosed before the age of 45. Similar patterns were observed for mortality from diabetic complications.
Conclusions: Patients with Type 2 diabetes have an increased risk of death.
|Authors||Barnett Karen N, Ogston Simon A, McMurdo Marion E T, Morris Andrew D, Evans Josie|
|Publication date online||20/02/2007|
|Publisher||Wiley-Blackwell for Diabetes UK|
Diabetic Medicine: Volume 24, Issue Supplement 1 (MAR 2007)