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Effect of the arachidonic acid/vitamin E interaction on the immune response of juvenile Atlantic salmon (Salmo salar) challenged against Piscirickettsia salmonis

Citation
Dantagnan P, Gonzalez K, Hevia M, Betancor M, Hernández A, Borquez A & Montero D (2017) Effect of the arachidonic acid/vitamin E interaction on the immune response of juvenile Atlantic salmon (Salmo salar) challenged against Piscirickettsia salmonis, Aquaculture Nutrition, 23 (4), pp. 710-720.

Abstract
Atlantic salmon (Salmo salar) were fed 6 experimental dietscontaining three levels of arachidonic acid (ARA) (0.18 g kg−1, 0.28 g kg−1 and 0.63 g kg−1 for low, medium and high levels, respectively) and two levels of vitamin E (150 and 730mg kg−1 for low and high levels, respectively). At the end of the experimental period, fatty acids in the liver and immunity markers (lysozyme activity, respiratory burst and phagocytic activity) were determined and fish subjected to a challenge test against the salmonid rickettsial syndrome (SRS) pathogen. ARA, vitamin E or their interaction did not exert an effect on fish performance, whereas ARA alone clearly increased the deposition of ARA. Dietary vitamin E only enhanced liver vitamin E deposition, while the interaction of ARA and vitamin E influenced lysozyme activity and EPA/ARA ratio pointing out the effect of both nutrients on the fish immune system and metabolism. Only the medium concentration contributed to reducing mortality when the fish were exposed to the SRS pathogen. In conclusion, different levels of supplementation with ARA and vitamin E in the diet had no effect on productivity, but did have effects on immune markers and cumulative mortality when fish were exposed to the SRS pathogen.

Keywords
arachidonic acid; Atlantic salmon; disease resistance; fish nutrition; health; vitamin E

StatusPublished
AuthorsDantagnan Patricio, Gonzalez Katerina, Hevia Martin, Betancor Monica, Hernández Adrián, Borquez Aliro, Montero Daniel
Publication date08/2017
Publication date online18/04/2016
Date accepted by journal15/12/2015
PublisherWiley-Blackwell
ISSN 1353-5773
LanguageEnglish

Journal
Aquaculture Nutrition: Volume 23, Issue 4

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